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Slay the Spire 2 New Bosses Guide
Updated 2026-06-02
New Bosses
- Thorn Matriarch (Act 1)
- Ashen Conductor (Act 2)
- Heart reworked (Act 4)
FAQ
- Hardest new boss?
- Reworked Heart.
- Old bosses returning?
- Most return, some reworked.
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